High-dose immunosuppressive therapy followed by stem cell transplant could soon be faced out. This is after it was recently found that this treatment procedure could cause sustained remission of multiple sclerosis (MS). The induced relapsing-remitting multiple sclerosis can trigger the immune system to attack the central nervous system.
After five years of research, 69 percent of the patients treated with high-dose immunosuppressive therapy (HDIT) and autologous hematopoietic cell transplant (HCT) survived without showing signs of multiple sclerosis or brain attack. This number of patients who survived didn’t take any MS medication after receiving HDIT/HCT treatment. The study dubbed as HALT-MS was sponsored by National Institute of Allergy and Infectious Diseases (NIAID). According to the survey, treatment with HDIT/HCT could be more efficient than the currently available medication for people with multiple sclerosis.
Efficacy and Safety of HDIT/HCT
During the study, 24 volunteers aged 26 to 52 years with relapsing-remitting MS were used as experimental units. The 24 volunteers were experiencing inflammation despite taking the best available medications for MS. The study aimed at suppressing active disease through the removal of disease-causing cells to reset the immune system. The patients’ blood-forming stem cells were first removed. The patients were then subjected to high-dose chemotherapy that depleted their immune system, and their stem cells returned to rebuild the immune system. Although three patients died, their death wasn’t related to HDIT/HCT treatment.
An In-Depth Look at Dr. Shiva Gopal Vasishta
Dr. Shiva Gopal Vasishta is a practicing neurologist in Voorhees, New Jersey. He is a graduate from Government Medical College Nagpur before completing a residency at Boston City Hospital. He has been practicing neurology for over 38 years. Dr. Shiva Gopal Vasishta also practices psychiatry.
Vasishta’s experience in the medical industry has earned him opportunities to serve at Kennedy University Hospital and Eastern Neurodiagnostic Association. The experienced neurologist is board certified neurology and accepts multiple insurance plans including Humana, and Horizon Blue Cross Blue Shield, Medicare. Besides his career, Dr. Shiva Gopal Vasishta supports his native language, Spanish.
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